⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561756 | 1.00 | — | — | |
| SCHEMBL301169 | 0.87 | — | — | |
| SCHEMBL301097 | 0.87 | — | — | |
| SCHEMBL31576112 | 0.84 | — | — | |
| SCHEMBL31627080 | 0.84 | — | — | |
| SCHEMBL289341 | 0.84 | — | — | |
| SCHEMBL301774 | 0.84 | — | — | |
| Hydrochloric Acid SCHEMBL17491862 | 0.78 | — | — | |
| SCHEMBL21178257 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL3494276 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12312373-B2 | Cyclopropane skeleton monophosphine ligands, palladium complexes thereof, preparation methods and application | NANKAI UNIVERSITY (CN) | 2025-05-27 | — | — | US | disclosed |
| US-20240376136-A1 | CYCLOPROPANE SKELETON MONOPHOSPHINE LIGANDS, PALLADIUM COMPLEXES THEREOF, PREPARATION METHODS AND APPLICATION | EXTRAORDINARY SYNERGY TECHNOLOGY (TIANJIN) CO., LTD (CN) | 2024-11-14 | — | — | US | disclosed |
| CN-116535439-B | Cyclopropane skeleton monophosphine ligand and palladium complex thereof, and preparation method and application thereof | 南开大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-116535439-A | Cyclopropane skeleton monophosphine ligand and palladium complex thereof, and preparation method and application thereof | 南开大学 | 2023-08-04 | — | — | CN | disclosed |
| EP-2610248-B1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE BY MEANS OF COUPLING METHOD USING A PALLADIUM COMPOUND | TEIJIN PHARMA LTD (JP) | 2016-06-08 | — | — | EP | disclosed |
| US-8952174-B2 | Process for producing phenyl-substituted heterocyclic derivative through coupling using transition metal catalyst | TEIJIN PHARMA LIMITED (JP) | 2015-02-10 | — | — | US | disclosed |
| CN-102333765-B | Process for producing phenyl-substituted heterocyclic derivative through coupling using transition metal catalyst | TEIJIN PHARMA LTD | 2015-01-14 | — | — | CN | disclosed |
| US-8916714-B2 | Method for producing phenyl-substituted heterocyclic derivative by means of coupling method using palladium compound | TEIJIN PHARMA LIMITED (JP) | 2014-12-23 | — | — | US | disclosed |
| EP-2610248-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE BY MEANS OF COUPLING METHOD USING A PALLADIUM COMPOUND | Teijin Pharma Limited (JP) | 2013-07-03 | — | — | EP | disclosed |
| US-20130158272-A1 | METHOD FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE BY MEANS OF COUPLING METHOD USING PALLADIUM COMPOUND | TEIJIN PHARMA LIMITED (JP) | 2013-06-20 | — | — | US | disclosed |
| CN-102333765-A | Process for producing phenyl-substituted heterocyclic derivative through coupling using transition metal catalyst | TEIJIN PHARMA LTD | 2012-01-25 | — | — | CN | disclosed |
| EP-2404908-A1 | PROCESS FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE THROUGH COUPLING USING TRANSITION METAL CATALYST | Teijin Pharma Limited (JP) | 2012-01-11 | — | — | EP | disclosed |
| US-20110313169-A1 | PROCESS FOR PRODUCING PHENYL-SUBSTITUTED HETEROCYCLIC DERIVATIVE THROUGH COUPLING USING TRANSITION METAL CATALYST | TEIJIN PHARMA LIMITED (JP) | 2011-12-22 | — | — | US | disclosed |