Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28871852 | 0.78 | HSD17B10 (0.69) | HSD17B10SOS1KDM4EALDH1A1HPGD | |
| SCHEMBL4846616 | 0.78 | HSD17B10 (0.53) | HSD17B10KDM4EALDH1A1HPGDPPARG | |
| SCHEMBL6316200 | 0.78 | HSD17B10 (0.56) | HSD17B10SOS1KDM4EALDH1A1HPGD | |
| SCHEMBL30157286 | 0.77 | HSD17B10 (0.32) | HSD17B10SOS1KDM4EALDH1A1HPGD | |
| SCHEMBL9449413 | 0.76 | PPARG (0.54) | HSD17B10SOS1KDM4EALDH1A1HPGD | |
| SCHEMBL1449076 | 0.71 | HSD17B10 (1.00) | HSD17B10KDM4EALDH1A1TSHRPTPN1 | |
| SCHEMBL30329399 | 0.71 | HSD17B10 (1.00) | HSD17B10KDM4EALDH1A1TSHRPTPN1 | |
| Hydrochloric Acid SCHEMBL11166393 | 0.69 | HSD17B10 (0.96) | HSD17B10KDM4EALDH1A1TSHRPTPN1 | |
| SCHEMBL1948692 | 0.69 | PTPN1 (0.63) | HSD17B10SOS1KDM4EALDH1A1HPGD | |
| SCHEMBL1551729 | 0.69 | PTPN1 (0.63) | HSD17B10SOS1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001123-A1 | NEW PYRIDOPYRIMIDINE DERIVATIVE | 上海艾力斯医药科技股份有限公司 | 2023-01-26 | — | — | WO | disclosed |