Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | EBP | Q15125 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157519 | 0.85 | CNR2 (0.45) | ALDH1A1HPGDTSHRSMN1; SMN2KMT2A | |
| SCHEMBL30157949 | 0.84 | CNR2 (0.44) | ALDH1A1HPGDTSHRSMN1; SMN2KMT2A | |
| SCHEMBL30158670 | 0.83 | PTGER2 (0.49) | ALDH1A1KMT2AMEN1PTGER2PTGDR | |
| SCHEMBL30157955 | 0.82 | POLB (0.39) | ALDH1A1SIGMAR1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL30157934 | 0.75 | KDM4E (0.51) | ALDH1A1HPGDCYP2C19SMN1; SMN2KMT2A | |
| SCHEMBL30157628 | 0.74 | EPHX2 (0.44) | TSHRKMT2AMEN1PTGER2PTGER3 | |
| SCHEMBL30157518 | 0.72 | KMT2A (0.51) | ALDH1A1CYP2C19SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL30157829 | 0.72 | KMT2A (0.51) | ALDH1A1CYP2C19SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL30157977 | 0.72 | KMT2A (0.51) | ALDH1A1CYP2C19SMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL30158532 | 0.70 | KMT2A (0.56) | ALDH1A1CYP2C19SMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |