Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157673 | 0.95 | KMT2A (0.50) | KMT2AGAAHDAC1HDAC2ALDH1A1 | |
| SCHEMBL30158505 | 0.91 | HDAC1 (0.46) | KMT2AGAAHDAC1HDAC2ALDH1A1 | |
| SCHEMBL30157549 | 0.91 | KMT2A (0.47) | KMT2AGAAHDAC1HDAC2ALDH1A1 | |
| SCHEMBL30157516 | 0.91 | KMT2A (0.47) | KMT2AGAAHDAC1HDAC2ALDH1A1 | |
| SCHEMBL30158564 | 0.90 | KMT2A (0.46) | KMT2AGAAHDAC1HDAC2ALDH1A1 | |
| SCHEMBL30157962 | 0.90 | GAA (0.51) | KMT2AGAAHDAC1HDAC2CYP2C19 | |
| SCHEMBL30157341 | 0.89 | KMT2A (0.45) | KMT2AGAAHDAC1HDAC2ALDH1A1 | |
| SCHEMBL30157974 | 0.89 | KMT2A (0.45) | KMT2AGAAHDAC1HDAC2ALDH1A1 | |
| SCHEMBL30157664 | 0.88 | GAA (0.50) | KMT2AGAAHDAC1HDAC2ALDH1A1 | |
| SCHEMBL30157747 | 0.87 | KMT2A (0.51) | KMT2AGAAHDAC1HDAC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |