Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK4 | Q16654 | 1/20 | 0.47 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26651022 | 1.00 | PDK4 (0.47) | PDK4JAK1HTR6SCN9ACNR1 | |
| SCHEMBL30088583 | 0.85 | PDK4 (0.48) | PDK4JAK1HTR6SCN9ACNR1 | |
| SCHEMBL26650792 | 0.85 | PDK4 (0.48) | PDK4JAK1HTR6SCN9ACNR1 | |
| SCHEMBL19297080 | 0.83 | PDK4 (0.58) | PDK4JAK1HTR6SCN9ACNR1 | |
| SCHEMBL19284668 | 0.79 | PDK4 (0.61) | PDK4JAK1HTR6SCN9ACNR1 | |
| SCHEMBL4888709 | 0.79 | CNR1 (0.53) | PDK4JAK1HTR6SCN9ACNR1 | |
| SCHEMBL30158364 | 0.79 | JAK1 (0.42) | PDK4JAK1HTR6SCN9ANAMPT | |
| SCHEMBL26650717 | 0.79 | JAK1 (0.42) | PDK4JAK1HTR6SCN9ANAMPT | |
| SCHEMBL12965676 | 0.78 | GRM1 (0.52) | PDK4JAK1HTR6SCN9ACNR1 | |
| SCHEMBL30158301 | 0.78 | BACE1 (0.43) | EEDRBBP4SUZ12EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4110459-A1 | HETEROCYCLIC AMIDES AND THEIR USE FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2023-01-04 | — | — | EP | disclosed |