Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 17/20 | 0.44 |
| ▸ | WDR77 | Q9BQA1 | 6/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24954131 | 1.00 | PRMT5 (0.44) | PRMT5WDR77CARM1PRMT1 | |
| SCHEMBL29119486 | 0.93 | PRMT5 (0.48) | PRMT5WDR77CARM1PRMT1 | |
| SCHEMBL30159326 | 0.93 | PRMT5 (0.48) | PRMT5WDR77CARM1PRMT1 | |
| SCHEMBL24954222 | 0.93 | PRMT5 (0.48) | PRMT5WDR77CARM1PRMT1 | |
| SCHEMBL29119484 | 0.93 | PRMT5 (0.48) | PRMT5WDR77CARM1PRMT1 | |
| SCHEMBL24954178 | 0.90 | PRMT5 (0.44) | PRMT5WDR77 | |
| SCHEMBL24954098 | 0.90 | PRMT5 (0.44) | PRMT5WDR77 | |
| SCHEMBL24954224 | 0.90 | PRMT5 (0.44) | PRMT5WDR77 | |
| SCHEMBL30159410 | 0.90 | PRMT5 (0.44) | PRMT5WDR77 | |
| SCHEMBL29119522 | 0.90 | PRMT5 (0.44) | PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117157297-A | PRMT5 inhibitors | 上海齐鲁制药研究中心有限公司 | 2023-12-01 | — | — | CN | disclosed |
| WO-2023001133-A1 | PRMT5 INHIBITOR | 上海齐鲁制药研究中心有限公司 | 2023-01-26 | — | — | WO | disclosed |