Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SELP | P16109 | 3/20 | 0.44 |
| ▸ | SELL | P14151 | 2/20 | 0.44 |
| ▸ | SELE | P16581 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10782436 | 1.00 | CETP (0.53) | CETPMAPK1SELPSELLSELE | |
| SCHEMBL19874824 | 1.00 | CETP (0.53) | CETPMAPK1SELPSELLSELE | |
| SCHEMBL18786584 | 0.99 | CETP (0.51) | CETPMAPK1SELPSELLSELE | |
| SCHEMBL17782908 | 0.99 | CETP (0.51) | CETPMAPK1SELPSELLSELE | |
| SCHEMBL17008954 | 0.99 | CETP (0.51) | CETPMAPK1SELPSELLSELE | |
| SCHEMBL1840886 | 0.99 | CETP (0.51) | CETPMAPK1SELPSELLSELE | |
| SCHEMBL1614746 | 0.99 | CETP (0.51) | CETPMAPK1SELPSELLSELE | |
| SCHEMBL15477780 | 0.99 | CETP (0.51) | CETPMAPK1SELPSELLSELE | |
| SCHEMBL9701069 | 0.96 | CETP (0.56) | CETPMAPK1SELPSELLSELE | |
| SCHEMBL7133066 | 0.94 | CETP (0.47) | CETPMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100197018-A1 | USE OF SUBSTRATES AS PHARMACOLOGICAL CHAPERONES | AMICUS THERAPEUTICS, INC. (US) | 2010-08-05 | — | — | US | claimed |
| EP-2137204-A1 | USE OF SUBSTRATES AS PHARMACOLOGICAL CHAPERONES | Amicus Therapeutics, Inc. (US) | 2009-12-30 | — | — | EP | claimed |
| WO-2008128089-A1 | USE OF SUBSTRATES AS PHARMACOLOGICAL CHAPERONES | AMICUS THERAPEUTICS, INC. (US) | 2008-10-23 | — | — | WO | claimed |
| US-10760112-B2 | Enzymatic activity assays for glucocerebrosidase | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2020-09-01 | — | — | US | disclosed |
| US-20180051315-A1 | ENZYMATIC ACTIVITY ASSAYS FOR GLUCOCEREBROSIDASE | SHIRE HUMAN GENETIC THERAPIES, INC. (US) | 2018-02-22 | — | — | US | disclosed |
| US-20100197018-A1 | USE OF SUBSTRATES AS PHARMACOLOGICAL CHAPERONES | AMICUS THERAPEUTICS, INC. (US) | 2010-08-05 | — | — | US | disclosed |