Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 8/20 | 0.59 |
| ▸ | JAK3 | P52333 | 18/20 | 0.52 |
| ▸ | LCK | P06239 | 16/20 | 0.52 |
| ▸ | EGFR | P00533 | 8/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24833188 | 0.96 | BTK (0.61) | BTKJAK3LCKEGFR | |
| SCHEMBL24833036 | 0.95 | BTK (0.59) | BTKJAK3LCKEGFR | |
| SCHEMBL24832958 | 0.93 | BTK (0.58) | BTKJAK3LCKEGFR | |
| SCHEMBL23460073 | 0.92 | JAK3 (0.62) | BTKJAK3LCKEGFR | |
| SCHEMBL29872130 | 0.92 | JAK3 (0.62) | BTKJAK3LCKEGFR | |
| SCHEMBL21855385 | 0.92 | JAK3 (0.62) | BTKJAK3LCKEGFR | |
| SCHEMBL24833040 | 0.92 | BTK (0.56) | BTKJAK3LCKEGFR | |
| SCHEMBL24833192 | 0.91 | BTK (0.66) | BTKJAK3LCKEGFR | |
| SCHEMBL21946785 | 0.90 | JAK3 (0.60) | BTKJAK3LCKEGFR | |
| SCHEMBL23484866 | 0.89 | JAK3 (0.59) | BTKJAK3LCKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274390-A1 | BRUTON'S TYROSINE KINASE AND MUTANT DEGRADER, COMPOSITION AND APPLICATION THEREOF | 杭州和正医药有限公司 | 2023-01-05 | — | — | WO | disclosed |