Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929803 | 0.83 | EGLN3 (0.59) | EGLN3ALDH1A1MAPTSMN1; SMN2TNKS2 | |
| SCHEMBL21233106 | 0.81 | CYP1A2 (0.48) | EGLN3MAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL4291632 | 0.79 | EGLN3 (0.69) | EGLN3ALDH1A1MAPTSMN1; SMN2TNKS2 | |
| SCHEMBL28263721 | 0.79 | EGLN3 (0.74) | EGLN3ALDH1A1MAPTSMN1; SMN2TNKS2 | |
| SCHEMBL18072254 | 0.79 | EGLN3 (0.62) | EGLN3ALDH1A1TNKS2MEN1KMT2A | |
| SCHEMBL7681770 | 0.78 | EGLN3 (0.53) | EGLN3ALDH1A1MAPTSMN1; SMN2TNKS2 | |
| SCHEMBL7197057 | 0.77 | EGLN3 (1.00) | EGLN3ALDH1A1TNKS2MEN1KMT2A | |
| SCHEMBL10514858 | 0.76 | EGLN3 (0.65) | EGLN3ALDH1A1MAPTSMN1; SMN2TNKS2 | |
| SCHEMBL1178524 | 0.76 | EGLN3 (0.69) | EGLN3ALDH1A1MAPTSMN1; SMN2TNKS2 | |
| Hydrochloric Acid SCHEMBL10637029 | 0.76 | EGLN3 (0.96) | EGLN3ALDH1A1TNKS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115955916-A | Active compound combinations | 拜耳公司 | 2023-04-11 | — | — | CN | disclosed |
| CN-115697059-A | Active compound combinations | 拜耳公司 | 2023-02-03 | — | — | CN | disclosed |