Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27198260 | 0.80 | TSHR (0.50) | TSHRALDH1A1KDM4EGLAGAA | |
| SCHEMBL22216857 | 0.77 | KDM4E (0.54) | TSHRALDH1A1KDM4EGLAGAA | |
| SCHEMBL31584153 | 0.77 | KDM4E (0.58) | TSHRALDH1A1KDM4EGLAGAA | |
| SCHEMBL30465534 | 0.77 | KDM4E (0.54) | TSHRALDH1A1KDM4EGLAGAA | |
| SCHEMBL19284336 | 0.77 | KDM4E (0.58) | TSHRALDH1A1KDM4EGLAGAA | |
| SCHEMBL22802075 | 0.76 | CA12 (0.42) | TSHRALDH1A1KDM4EGLAGAA | |
| SCHEMBL25225193 | 0.76 | KDM4E (0.43) | TSHRALDH1A1KDM4EGLAGAA | |
| SCHEMBL23674709 | 0.76 | TSHR (0.42) | TSHRALDH1A1KDM4EGLAGAA | |
| SCHEMBL31149578 | 0.76 | TSHR (0.39) | TSHRALDH1A1KDM4EGLAGAA | |
| SCHEMBL23449164 | 0.76 | TSHR (0.39) | TSHRALDH1A1KDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697059-A | Active compound combinations | 拜耳公司 | 2023-02-03 | — | — | CN | disclosed |