Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 5/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | STS | P08842 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22129876 | 1.00 | SIRT2 (0.47) | SIRT2ESR1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL30162752 | 0.96 | ESR1 (0.46) | SIRT2ESR1STSALDH1A1 | |
| SCHEMBL22129887 | 0.96 | ESR1 (0.46) | SIRT2ESR1STSALDH1A1 | |
| SCHEMBL22129868 | 0.89 | SIRT2 (0.49) | SIRT2ESR1NPC1MAPTRAB9A | |
| SCHEMBL30162785 | 0.89 | SIRT2 (0.49) | SIRT2ESR1NPC1MAPTRAB9A | |
| SCHEMBL28988280 | 0.88 | ESR1 (0.49) | SIRT2ESR1STSHDAC6 | |
| SCHEMBL22129871 | 0.87 | ESR1 (0.46) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL30404913 | 0.87 | ESR1 (0.46) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL21630161 | 0.86 | STS (0.49) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL29881106 | 0.86 | STS (0.49) | ESR1AKR1C4AKR1C3AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227158-B | Curable composition for optical material and optical material | 株式会社德山 | 2023-04-25 | — | — | CN | disclosed |
| CN-113166311-B | Composition for optical material and optical material | 株式会社德山 | 2023-01-06 | — | — | CN | disclosed |