Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TIPARP | Q7Z3E1 | 9/20 | 0.75 |
| ▸ | PARP1 | P09874 | 4/20 | 0.49 |
| ▸ | SLC6A7 | Q99884 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968300 | 1.00 | TIPARP (0.75) | TIPARPPARP1SLC6A7KDM4EMGLL | |
| SCHEMBL30165104 | 0.87 | TIPARP (0.57) | TIPARPPARP1SLC6A7 | |
| SCHEMBL24968898 | 0.87 | TIPARP (0.57) | TIPARPPARP1SLC6A7 | |
| SCHEMBL24968384 | 0.86 | TIPARP (0.59) | TIPARPPARP1SLC6A7 | |
| SCHEMBL25270477 | 0.86 | TIPARP (1.00) | TIPARPPARP1 | |
| SCHEMBL24968878 | 0.85 | TIPARP (0.57) | TIPARPPARP1 | |
| SCHEMBL24968427 | 0.80 | TIPARP (0.62) | TIPARPPARP1SLC6A7KDM4EMGLL | |
| SCHEMBL30165056 | 0.80 | TIPARP (0.62) | TIPARPPARP1SLC6A7KDM4EMGLL | |
| SCHEMBL25229125 | 0.80 | TIPARP (0.77) | TIPARPPARP1 | |
| SCHEMBL24968208 | 0.80 | TIPARP (0.59) | TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |