Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23744093 | 1.00 | HTR2C (0.41) | HTR2CACVR1HDAC1SLC6A9CHRM2 | |
| SCHEMBL28966669 | 1.00 | HTR2C (0.41) | HTR2CACVR1HDAC1SLC6A9CHRM2 | |
| SCHEMBL28966553 | 1.00 | HTR2C (0.41) | HTR2CACVR1HDAC1SLC6A9CHRM2 | |
| SCHEMBL18826007 | 0.84 | EIF2AK4 (0.42) | HDAC1SLC6A9CHRM2CHRM1CHRM5 | |
| SCHEMBL23489511 | 0.84 | EIF2AK4 (0.42) | HDAC1SLC6A9CHRM2CHRM1CHRM5 | |
| SCHEMBL23489757 | 0.84 | EIF2AK4 (0.42) | HDAC1SLC6A9CHRM2CHRM1CHRM5 | |
| SCHEMBL29861831 | 0.84 | EIF2AK4 (0.42) | HDAC1SLC6A9CHRM2CHRM1CHRM5 | |
| Hydrochloric Acid SCHEMBL23459167 | 0.82 | EIF2AK4 (0.41) | HDAC1SLC6A9CHRM2CHRM1CHRM5 | |
| Hydrochloric Acid SCHEMBL23459166 | 0.82 | EIF2AK4 (0.41) | HDAC1SLC6A9CHRM2CHRM1CHRM5 | |
| SCHEMBL12683436 | 0.82 | CHRM2 (0.43) | SLC6A9CHRM2CHRM1CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745971-B | PARP7 inhibitor and application thereof | 北京华森英诺生物科技有限公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-115745971-A | PARP7 inhibitor and application thereof | 重庆华森制药股份有限公司 | 2023-03-07 | — | — | CN | disclosed |