Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5416326 | 1.00 | MEN1 (0.44) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL2714124 | 0.78 | KMT2A (0.56) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL6073354 | 0.78 | MEN1 (0.38) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL9153248 | 0.77 | MEN1 (0.38) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL3257090 | 0.77 | KMT2A (0.46) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL22648382 | 0.76 | MEN1 (0.42) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL5912611 | 0.76 | AURKA (0.41) | MEN1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL19725082 | 0.75 | MEN1 (0.49) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL6524904 | 0.75 | KMT2A (0.44) | MEN1KMT2AMAPTLMNAALDH1A1 | |
| SCHEMBL1493979 | 0.75 | KMT2A (0.44) | MEN1KMT2AMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4125845-A1 | NOVEL 2-PYRIMIDONE ANALOGS AS POTENT ANTIVIRAL AGENTS AGAINST ALPHAVIRUSES | Southern Research Institute (US) | 2023-02-08 | — | — | EP | disclosed |