Adenosine

Adenosine

SCHEMBL30165600

Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O.O=P([O-])([O-])OP(=O)(O)OP(=O)(O)O.[Na+].[Na+]

nearest known ligand 0.75

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Known targets — ChEMBL curated mechanism

ADORA1ADORA2AADORA2BADORA3

The experimentally established mechanism targets of Adenosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA1 known ✓ P30542 3/20 0.72
ADORA3 known ✓ P0DMS8 1/20 0.72
ADORA2A known ✓ P29274 1/20 0.72
ADORA2B known ✓ P29275 1/20 0.72
P2RY2 P41231 4/20 0.75
SMN1; SMN2 Q16637 3/20 0.72
DPP4 P27487 1/20 0.72
MEN1 O00255 1/20 0.72
SLC28A1 O00337 1/20 0.72
MAP3K7 O43318 1/20 0.72
SLC28A2 O43868 1/20 0.72
GAPDH P04406 1/20 0.72
MAPK1 P28482 1/20 0.72
STAT6 P42226 1/20 0.72
PI4KA P42356 1/20 0.72
KMT2A Q03164 1/20 0.72
PI4K2B Q8TCG2 1/20 0.72
DOT1L Q8TEK3 1/20 0.72
SLC29A1 Q99808 1/20 0.72
PI4K2A Q9BTU6 1/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenosine SCHEMBL30165599 1.00 P2RY2 (0.75) P2RY2ADORA1SMN1; SMN2DPP4MEN1
Adenosine SCHEMBL4762694 1.00 P2RY2 (0.75) P2RY2ADORA1SMN1; SMN2DPP4MEN1
Adenosine SCHEMBL31380122 0.99 P2RY2 (0.74) P2RY2ADORA1SMN1; SMN2DPP4MEN1
Adenosine SCHEMBL27880243 0.99 P2RY2 (0.74) P2RY2ADORA1SMN1; SMN2DPP4MEN1
Adenosine SCHEMBL28424876 0.99 P2RY2 (0.74) P2RY2ADORA1SMN1; SMN2DPP4MEN1
Adenosine SCHEMBL28417436 0.99 P2RY2 (0.74) P2RY2ADORA1SMN1; SMN2DPP4MEN1
Adenosine SCHEMBL5495320 0.96 ADORA1 (0.75) P2RY2ADORA1SMN1; SMN2DPP4MEN1
Adenosine SCHEMBL28652247 0.95 P2RY2 (0.74) P2RY2ADORA1SMN1; SMN2DPP4MEN1
Adenosine SCHEMBL2248155 0.95 ADORA1 (0.74) P2RY2ADORA1SMN1; SMN2DPP4MEN1
Adenosine SCHEMBL31308570 0.95 ADORA1 (0.74) P2RY2ADORA1SMN1; SMN2DPP4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112375509-B Environment-friendly bio-oil starch adhesive and preparation method thereof 浙江荣禾新材料股份有限公司 2023-01-06 CN claimed
CN-119432960-A Method for preparing oxidized nicotinamide adenine dinucleotide phosphate by double-enzyme coupling 浙江工业大学 2025-02-14 CN disclosed
CN-116411038-A Method for preparing nicotinamide adenine dinucleotide phosphate by using enzyme method 湖南利尔生物科技有限公司 2023-07-11 CN disclosed
CN-115785851-A Environment-friendly bio-oil starch adhesive 简杰 2023-03-14 CN disclosed
CN-112375509-B Environment-friendly bio-oil starch adhesive and preparation method thereof 浙江荣禾新材料股份有限公司 2023-01-06 CN disclosed