Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 20/20 | 0.67 |
| ▸ | LCK | P06239 | 18/20 | 0.67 |
| ▸ | EGFR | P00533 | 5/20 | 0.67 |
| ▸ | BTK | Q06187 | 7/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24833226 | 1.00 | JAK3 (0.67) | JAK3LCKEGFRBTK | |
| SCHEMBL24833227 | 0.90 | JAK3 (0.57) | JAK3LCKEGFRBTK | |
| SCHEMBL24833610 | 0.86 | JAK3 (0.87) | JAK3LCKEGFRBTK | |
| SCHEMBL24832894 | 0.85 | JAK3 (0.70) | JAK3LCKEGFRBTK | |
| SCHEMBL24832883 | 0.82 | JAK3 (0.82) | JAK3LCKEGFRBTK | |
| SCHEMBL24833229 | 0.81 | JAK3 (0.64) | JAK3LCKEGFRBTK | |
| SCHEMBL24834069 | 0.80 | JAK3 (0.69) | JAK3LCKEGFRBTK | |
| SCHEMBL16763891 | 0.80 | JAK3 (1.00) | JAK3LCKEGFRBTK | |
| SCHEMBL29871796 | 0.80 | JAK3 (1.00) | JAK3LCKEGFRBTK | |
| SCHEMBL16763889 | 0.80 | JAK3 (1.00) | JAK3LCKEGFRBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115557933-B | Bruton tyrosine kinase and mutant degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-115557933-A | Bruton tyrosine kinase and mutant degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-01-03 | — | — | CN | disclosed |