SCHEMBL301659

SCHEMBL301659

CCCCCCCCCCCCCCCCOC1O[C@H](C)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.67

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 3/20 0.55
MAPK1 P28482 1/20 0.44
IGF2R P11717 4/20 0.43
SELL P14151 6/20 0.43
SELP P16109 6/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15618346 1.00 GBA1 (0.55) GBA1MAPK1IGF2RSELLSELP
SCHEMBL17188539 1.00 GBA1 (0.55) GBA1MAPK1IGF2RSELLSELP
SCHEMBL15618340 1.00 GBA1 (0.55) GBA1MAPK1IGF2RSELLSELP
SCHEMBL15618301 1.00 GBA1 (0.55) GBA1MAPK1IGF2RSELLSELP
SCHEMBL2784705 1.00 GBA1 (0.55) GBA1MAPK1IGF2RSELLSELP
SCHEMBL15618428 1.00 GBA1 (0.55) GBA1MAPK1IGF2RSELLSELP
SCHEMBL15618302 1.00 GBA1 (0.55) GBA1MAPK1IGF2RSELLSELP
SCHEMBL15618429 1.00 GBA1 (0.55) GBA1MAPK1IGF2RSELLSELP
SCHEMBL5689541 1.00 GBA1 (0.55) GBA1MAPK1IGF2RSELLSELP
SCHEMBL15870699 1.00 GBA1 (0.55) GBA1MAPK1IGF2RSELLSELP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4851946-B2 2012-01-11 JP claimed
EP-1706415-B1 LIPID- DERIVATIZED BISPHOSPHONIC ACID MCS MICRO CARRIER SYSTEMS GMBH (DE) 2011-10-05 EP claimed
EP-1706415-A1 LIPID- DERIVATIZED BISPHOSPHONIC ACID MCS Micro Carrier Systems GmbH (DE) 2006-10-04 EP claimed
WO-2005070952-A1 LIPID- DERIVATIZED BISPHOSPHONIC ACID MCS MICRO CARRIER SYSTEMS GMBH (DE) 2005-08-04 WO claimed
EP-1706415-B1 LIPID- DERIVATIZED BISPHOSPHONIC ACID MCS MICRO CARRIER SYSTEMS GMBH (DE) 2011-10-05 EP disclosed
EP-1706415-A1 LIPID- DERIVATIZED BISPHOSPHONIC ACID MCS Micro Carrier Systems GmbH (DE) 2006-10-04 EP disclosed
WO-2005070952-A1 LIPID- DERIVATIZED BISPHOSPHONIC ACID MCS MICRO CARRIER SYSTEMS GMBH (DE) 2005-08-04 WO disclosed