Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | BCR | P11274 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24054006 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTRPS6KA5NOTUMABL1 | |
| SCHEMBL24054153 | 0.76 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTRPS6KA5ABL1BCR | |
| SCHEMBL31205839 | 0.73 | SMN1; SMN2 (0.49) | SMN1; SMN2MAPTRPS6KA5ABL1BCR | |
| SCHEMBL25695707 | 0.72 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTRPS6KA5ABL1BCR | |
| SCHEMBL31205699 | 0.70 | RPS6KA5 (0.52) | SMN1; SMN2MAPTRPS6KA5ALDH1A1L3MBTL1 | |
| SCHEMBL473450 | 0.69 | RPS6KA5 (0.51) | SMN1; SMN2MAPTRPS6KA5ALDH1A1L3MBTL1 | |
| SCHEMBL17601113 | 0.68 | IDH1 (0.43) | MAPTRPS6KA5NOTUMALDH1A1L3MBTL1 | |
| SCHEMBL24053482 | 0.68 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTRPS6KA5ALDH1A1L3MBTL1 | |
| SCHEMBL1186659 | 0.66 | — | — | |
| SCHEMBL30166311 | 0.66 | KMT2A (0.56) | SMN1; SMN2MAPTALDH1A1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115697991-B | Piperazine cyclic ureas | 维泰瑞隆有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-115697991-A | Piperazine cyclic ureas | 维泰瑞隆有限公司 | 2023-02-03 | — | — | CN | disclosed |