Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.69 |
| ▸ | MAPT | P10636 | 6/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.69 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | LDHA | P00338 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CLK1 | P49759 | 1/20 | 0.56 |
| ▸ | CASP3 | P42574 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24812486 | 1.00 | MEN1 (0.69) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL28648254 | 0.86 | MEN1 (0.62) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL30166738 | 0.86 | MEN1 (0.62) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL30166743 | 0.85 | MEN1 (0.64) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL28651370 | 0.85 | MEN1 (0.64) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL30166745 | 0.84 | MEN1 (0.61) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL28656599 | 0.84 | MEN1 (0.61) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL28638012 | 0.84 | MEN1 (0.62) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL30166723 | 0.84 | MEN1 (0.62) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL24812919 | 0.83 | MEN1 (0.61) | MEN1KMT2AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112812111-B | Benzothiazole compound and medical application thereof | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |