SCHEMBL30167263

SCHEMBL30167263

C=CCC1(C)NCCc2c(Cl)cccc21

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.38
HTR2C P28335 1/20 0.38
ADRA2A P08913 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
PNMT P11086 1/20 0.33
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32
PGR P06401 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28946032 1.00 KDM1A (0.38) KDM1AHTR2CADRA2AADRA2BADRA2C
SCHEMBL175960 0.77 MEN1 (0.39)
Hydrochloric Acid SCHEMBL9374010 0.69 KDM1A (0.37) KDM1AHTR2CPNMTGRIN1GRIN2A
SCHEMBL5678916 0.67 HTR2C (0.51) KDM1AHTR2CADRA2AADRA2BADRA2C
SCHEMBL19764440 0.62 KDM1A (0.71) KDM1AHTR2CADRA2AADRA2BADRA2C
SCHEMBL24542924 0.61 KDM1A (0.51) KDM1AHTR2CADRA2AADRA2BADRA2C
SCHEMBL28884789 0.61 KDM1A (0.51) KDM1AHTR2CADRA2AADRA2BADRA2C
SCHEMBL24542932 0.61 KDM1A (0.47) KDM1AADRA2AADRA2BADRA2CGRIN1
SCHEMBL8817015 0.61 MEN1 (0.40) HTR2CADRA2AADRA2BADRA2CPNMT
SCHEMBL26297132 0.60 KDM1A (0.50) KDM1AHTR2CADRA2AADRA2BADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115650824-B Chiral diol and preparation method thereof, prepared catalyst and preparation method and application thereof 合肥工业大学 2024-01-23 CN disclosed
CN-115650824-A Chiral diol and preparation method thereof, prepared catalyst, preparation method and application 合肥工业大学 2023-01-31 CN disclosed