Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BCL6 | P41182 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24105243 | 1.00 | PTK6 (0.40) | PTK6KMT2AAURKBAURKAALDH1A1 | |
| SCHEMBL24104694 | 0.96 | PTK6 (0.38) | PTK6KMT2AAURKBAURKAALDH1A1 | |
| SCHEMBL30167855 | 0.96 | PTK6 (0.38) | PTK6KMT2AAURKBAURKAALDH1A1 | |
| SCHEMBL30167729 | 0.91 | PTK6 (0.41) | PTK6KMT2AAURKBAURKAALDH1A1 | |
| SCHEMBL24105198 | 0.91 | PTK6 (0.41) | PTK6KMT2AAURKBAURKAALDH1A1 | |
| SCHEMBL24105246 | 0.91 | PTK6 (0.38) | PTK6KMT2AAURKBAURKAALDH1A1 | |
| SCHEMBL30167773 | 0.91 | PTK6 (0.38) | PTK6KMT2AAURKBAURKAALDH1A1 | |
| SCHEMBL25170711 | 0.91 | KMT2A (0.38) | PTK6KMT2AAURKBAURKAALDH1A1 | |
| Hydrochloric Acid SCHEMBL25173779 | 0.90 | PTK6 (0.41) | PTK6KMT2AAURKBAURKAALDH1A1 | |
| SCHEMBL25177003 | 0.90 | PTK6 (0.39) | PTK6AURKBAURKAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667264-A | Novel imidazo-pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-115667264-A | Novel imidazo-pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | disclosed |