Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 5/20 | 0.41 |
| ▸ | KDR | P35968 | 7/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.38 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.37 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24105238 | 1.00 | TTK (0.41) | TTKKDRAURKAZAP70KARS1 | |
| Hydrochloric Acid SCHEMBL30168139 | 0.99 | TTK (0.40) | TTKKDRAURKAZAP70KARS1 | |
| Trifluoroacetic Acid SCHEMBL30168162 | 0.95 | TTK (0.38) | TTKKDRAURKAZAP70KARS1 | |
| SCHEMBL30371277 | 0.87 | BRD4 (0.42) | TTKKDRAURKAEGFRTNIK | |
| SCHEMBL24105221 | 0.87 | KDR (0.45) | TTKKDRAURKAEGFRALDH1A1 | |
| SCHEMBL24104678 | 0.85 | TTK (0.44) | TTKKDRAURKAEGFRALDH1A1 | |
| SCHEMBL30168196 | 0.85 | TTK (0.44) | TTKKDRAURKAEGFRALDH1A1 | |
| SCHEMBL22124744 | 0.82 | TTK (0.45) | TTKMAPKAPK5PTK6 | |
| SCHEMBL24105192 | 0.82 | PTK6 (0.47) | TTKKDREGFRALDH1A1PTK6 | |
| Hydrochloric Acid SCHEMBL30171610 | 0.82 | TTK (0.45) | TTKMAPKAPK5PTK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667264-A | Novel imidazo-pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | claimed |
| CN-115667264-A | Novel imidazo-pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | disclosed |