Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 2/20 | 0.45 |
| ▸ | FYN | P06241 | 3/20 | 0.44 |
| ▸ | STK4 | Q13043 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 4/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 5/20 | 0.38 |
| ▸ | KDR | P35968 | 5/20 | 0.38 |
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | ROS1 | P08922 | 1/20 | 0.37 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.37 |
| ▸ | IGF1R | P08069 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24105033 | 1.00 | PTK6 (0.45) | PTK6FYNSTK4TTKMC4R | |
| SCHEMBL24105229 | 0.93 | PTK6 (0.49) | PTK6FYNSTK4TTKMC4R | |
| SCHEMBL30168157 | 0.93 | PTK6 (0.49) | PTK6FYNSTK4TTKMC4R | |
| SCHEMBL30371857 | 0.90 | PTK6 (0.46) | PTK6FYNSTK4TTKMC4R | |
| SCHEMBL25447277 | 0.90 | PTK6 (0.46) | PTK6FYNSTK4TTKMC4R | |
| SCHEMBL24105218 | 0.88 | PTK6 (0.47) | PTK6FYNTTKEGFRKDR | |
| SCHEMBL30168129 | 0.88 | TTK (0.45) | PTK6FYNTTKMC4R | |
| SCHEMBL24104766 | 0.88 | TTK (0.45) | PTK6FYNTTKMC4R | |
| SCHEMBL25167794 | 0.82 | PTK6 (0.46) | PTK6TTKKDRAURKBIGF1R | |
| SCHEMBL30168204 | 0.82 | PTK6 (0.46) | PTK6TTKKDRAURKBIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667264-A | Novel imidazo-pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | disclosed |