SCHEMBL30168930

SCHEMBL30168930

N#Cc1cccc(-c2ccc3c(c2)CN(C2CCC(=O)NC2=O)C3=O)n1

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 10/20 0.56
IKZF2 Q9UKS7 9/20 0.52
IKZF1 Q13422 1/20 0.51
CSNK1A1 P48729 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23861021 1.00 CRBN (0.56) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL27313199 0.88 CRBN (0.48) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL27323622 0.88 CRBN (0.48) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL27313973 0.87 CRBN (0.47) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL27322782 0.87 CRBN (0.47) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL30133238 0.87 CRBN (0.58) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL23860847 0.87 CRBN (0.58) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL23860893 0.85 CRBN (0.65) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL30930655 0.85 CRBN (0.65) CRBNIKZF2IKZF1CSNK1A1
SCHEMBL30133310 0.85 CRBN (0.65) CRBNIKZF2IKZF1CSNK1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4126843-B1 SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER BRISTOL MYERS SQUIBB CO (US) 2026-02-11 EP claimed
EP-4126843-A1 SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER Bristol-Myers Squibb Company (US) 2023-02-08 EP disclosed