⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13744834 | 1.00 | — | — | |
| SCHEMBL3045826 | 0.81 | — | — | |
| SCHEMBL151114 | 0.81 | — | — | |
| SCHEMBL27651209 | 0.78 | HSP90AA1 (0.56) | — | |
| Ammonia Solution, Strong SCHEMBL20919221 | 0.78 | HSP90AA1 (0.56) | — | |
| SCHEMBL30863954 | 0.78 | HSP90AA1 (0.56) | — | |
| SCHEMBL1755602 | 0.75 | — | — | |
| SCHEMBL29879751 | 0.75 | — | — | |
| SCHEMBL958039 | 0.74 | — | — | |
| SCHEMBL879566 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111582-A1 | AZA-TETRACYCLIC OXAZEPINE INHIBITORS OF KRAS-G12D | GENENTECH, INC. (US) | 2025-05-30 | — | — | WO | disclosed |
| CN-115605466-B | Substituted oxoisoindoline compounds for the treatment of cancer | 百时美施贵宝公司 | 2024-11-01 | — | — | CN | disclosed |
| EP-4126843-A1 | SUBSTITUTED OXOISOINDOLINE COMPOUNDS FOR THE TREATMENT OF CANCER | Bristol-Myers Squibb Company (US) | 2023-02-08 | — | — | EP | disclosed |