Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.47 |
| ▸ | REN | P00797 | 4/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PEPD | P12955 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29649137 | 0.90 | ACE (0.48) | ACERENDPP4FAPDPP8 | |
| SCHEMBL29765255 | 0.88 | CAPN1 (0.47) | ACERENDPP4FAPDPP8 | |
| SCHEMBL30800861 | 0.87 | DPP4 (0.43) | RENDPP4FAPDPP8DPP9 | |
| SCHEMBL30800862 | 0.85 | DPP4 (0.46) | ACERENDPP4FAPDPP8 | |
| SCHEMBL29765249 | 0.84 | CAPN1 (0.47) | ACERENKDM4EF2LMNA | |
| SCHEMBL29765105 | 0.84 | CAPN1 (0.47) | ACERENKDM4EF2LMNA | |
| SCHEMBL29765170 | 0.84 | CAPN1 (0.47) | ACERENKDM4EF2LMNA | |
| SCHEMBL29765258 | 0.84 | CAPN1 (0.47) | ACERENKDM4EF2LMNA | |
| SCHEMBL29765176 | 0.84 | CAPN1 (0.47) | ACERENKDM4EF2LMNA | |
| SCHEMBL29630804 | 0.84 | ACE (0.44) | ACERENDPP4FAPDPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240270801-A1 | EPITOPE PEPTIDE OF HUMAN ALPHA-SYNUCLEIN AND PHARMACEUTICAL COMPOSITION INCLUDING SAID PEPTIDE | Sumitomo Pharma Co., Ltd. (JP) | 2024-08-15 | — | — | US | disclosed |
| EP-4357354-A1 | EPITOPE PEPTIDE OF HUMAN ALPHA-SYNUCLEIN AND PHARMACEUTICAL COMPOSITION INCLUDING SAID PEPTIDE | Sumitomo Pharma Co., Ltd. (JP) | 2024-04-24 | — | — | EP | disclosed |
| WO-2022265091-A1 | EPITOPE PEPTIDE OF HUMAN α-SYNUCLEIN AND PHARMACEUTICAL COMPOSITION INCLUDING SAID PEPTIDE | 住友ファーマ株式会社 | 2022-12-22 | — | — | WO | disclosed |