SCHEMBL30169818

SCHEMBL30169818

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ERAP2 Q6P179 7/20 0.64
ECE1 P42892 6/20 0.62
KDM4E B2RXH2 2/20 0.59
MAPT P10636 2/20 0.59
MEN1 O00255 1/20 0.59
LMNA P02545 1/20 0.59
MPO P05164 1/20 0.59
TSHR P16473 1/20 0.59
BLM P54132 1/20 0.59
PMP22 Q01453 1/20 0.59
KMT2A Q03164 1/20 0.59
HIF1A Q16665 1/20 0.59
IL1RN P18510 7/20 0.59
ERAP1 Q9NZ08 3/20 0.59
ACE P12821 2/20 0.58
APAF1 O14727 1/20 0.56
POLB P06746 1/20 0.56
RECQL P46063 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30051718 1.00 ERAP2 (0.64) ERAP2ECE1KDM4EMAPTMEN1
SCHEMBL29538468 0.94 ERAP2 (0.69) ERAP2ECE1KDM4EMAPTMEN1
SCHEMBL30051546 0.93 ERAP2 (0.73) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL29531276 0.93 ERAP2 (0.73) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL29531545 0.93 ERAP2 (0.73) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL30051359 0.93 ACE (0.64) ERAP2ECE1KDM4EMAPTMEN1
SCHEMBL30051545 0.92 ECE1 (0.65) ERAP2ECE1KDM4EMAPTMEN1
SCHEMBL30050850 0.92 ECE1 (0.65) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL7622341 0.92 ECE1 (0.70) ERAP2ECE1KDM4EMAPTMEN1
SCHEMBL30991071 0.92 ECE1 (0.70) ERAP2ECE1KDM4EMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023207107-A1 GLP-1/GCG RECEPTOR CO-AGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME AND USE THEREOF 苏州星洲生物科技有限公司 2023-11-02 WO claimed
WO-2023139106-A2 LONG-ACTING GIPR ANTAGONISTS NOVO NORDISK A/S (DK) 2023-07-27 WO claimed
US-20230143604-A1 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-05-11 US claimed
CN-115916812-A GIP receptor agonist peptide compounds and uses thereof 武田药品工业株式会社 2023-04-04 CN claimed
EP-4126920-A2 GIF RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF Takeda Pharmaceutical Company Limited (JP) 2023-02-08 EP claimed
WO-2023207107-A1 GLP-1/GCG RECEPTOR CO-AGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME AND USE THEREOF 苏州星洲生物科技有限公司 2023-11-02 WO disclosed
WO-2023139106-A2 LONG-ACTING GIPR ANTAGONISTS NOVO NORDISK A/S (DK) 2023-07-27 WO disclosed
US-20230143604-A1 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-05-11 US disclosed
CN-115916812-A GIP receptor agonist peptide compounds and uses thereof 武田药品工业株式会社 2023-04-04 CN disclosed
EP-4126920-A2 GIF RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF Takeda Pharmaceutical Company Limited (JP) 2023-02-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230143604-A1 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF GIPR, GLP1R, GRPR ERAP2 552/4885ECE1 1643/4885KDM4E 4782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.