SCHEMBL30169836

SCHEMBL30169836

CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(N)=O)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ERAP2 Q6P179 9/20 0.63
ECE1 P42892 5/20 0.56
IL1RN P18510 8/20 0.56
ERAP1 Q9NZ08 5/20 0.56
NPBWR1 P48145 1/20 0.54
KISS1R Q969F8 2/20 0.53
ACE P12821 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29376316 0.96 ERAP2 (0.67) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL29947263 0.95 ACE (0.58) ERAP2ECE1ACE
SCHEMBL30511104 0.93 ERAP2 (0.62) ERAP2ECE1IL1RNERAP1KISS1R
SCHEMBL20764526 0.93 ERAP2 (0.70) ERAP2ECE1IL1RNERAP1KISS1R
SCHEMBL30219046 0.93 ERAP2 (0.68) ERAP2ECE1IL1RNERAP1KISS1R
SCHEMBL31343242 0.91 ERAP2 (0.62) ERAP2ECE1IL1RNERAP1KISS1R
SCHEMBL29354013 0.90 ERAP2 (0.76) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL30051545 0.90 ECE1 (0.65) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL21641798 0.89 KDM4E (0.62) ERAP2ECE1ACE
SCHEMBL5970454 0.89 KDM4E (0.62) ERAP2ECE1ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230143604-A1 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-05-11 US claimed
CN-115916812-A GIP receptor agonist peptide compounds and uses thereof 武田药品工业株式会社 2023-04-04 CN claimed
EP-4126920-A2 GIF RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF Takeda Pharmaceutical Company Limited (JP) 2023-02-08 EP claimed
CN-118852453-A Incretin analogue, preparation method and application thereof 上海多米瑞生物技术有限公司 2024-10-29 CN disclosed
US-20230143604-A1 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-05-11 US disclosed
CN-115916812-A GIP receptor agonist peptide compounds and uses thereof 武田药品工业株式会社 2023-04-04 CN disclosed
EP-4126920-A2 GIF RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF Takeda Pharmaceutical Company Limited (JP) 2023-02-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230143604-A1 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF GIPR, GLP1R, GRPR ERAP2 552/4885ECE1 1643/4885IL1RN 353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.