Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 0.72 |
| ▸ | NTRK1 | P04629 | 16/20 | 0.70 |
| ▸ | NTRK2 | Q16620 | 16/20 | 0.70 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16763076 | 1.00 | CSF1R (0.72) | CSF1RNTRK1NTRK2NTRK3 | |
| SCHEMBL16763070 | 0.88 | CSF1R (0.72) | CSF1RNTRK1NTRK2NTRK3 | |
| SCHEMBL16763065 | 0.85 | CSF1R (0.76) | CSF1RNTRK1NTRK2NTRK3 | |
| SCHEMBL16763104 | 0.83 | CSF1R (0.76) | CSF1RNTRK1NTRK2NTRK3 | |
| Gz-389988 SCHEMBL29589607 | 0.83 | CSF1R (1.00) | CSF1RNTRK1NTRK2NTRK3 | |
| Gz-389988 SCHEMBL16762937 | 0.83 | CSF1R (1.00) | CSF1RNTRK1NTRK2NTRK3 | |
| Gz-389988 SCHEMBL29774374 | 0.83 | CSF1R (1.00) | CSF1RNTRK1NTRK2NTRK3 | |
| Water SCHEMBL25176420 | 0.82 | CSF1R (0.80) | CSF1RNTRK1NTRK2NTRK3 | |
| Gz-389988 SCHEMBL17843975 | 0.82 | CSF1R (0.98) | CSF1RNTRK1NTRK2NTRK3 | |
| Gz-389988 SCHEMBL31167982 | 0.82 | CSF1R (0.98) | CSF1RNTRK1NTRK2NTRK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110950862-B | Pharmaceutical formulations of tropomyosin-related kinase (TRK) inhibitors | 建新公司 | 2024-01-05 | — | — | CN | disclosed |
| EP-4110772-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | Cullgen (Shanghai), Inc. (CN) | 2023-01-04 | — | — | EP | disclosed |