Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 10/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | EDNRB | P24530 | 4/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30296194 | 0.94 | EDNRA (0.51) | EDNRAAGTR1EDNRB | |
| SCHEMBL30295907 | 0.89 | EDNRA (0.47) | EDNRAAGTR1EDNRB | |
| SCHEMBL30844585 | 0.89 | EDNRA (0.47) | EDNRAAGTR1EDNRB | |
| SCHEMBL31229191 | 0.89 | EDNRA (0.57) | EDNRAAGTR1EDNRB | |
| SCHEMBL31229092 | 0.89 | EDNRA (0.57) | EDNRAAGTR1EDNRB | |
| SCHEMBL30296109 | 0.89 | EDNRA (0.48) | EDNRAAGTR1EDNRBCCNT1CDK9 | |
| SCHEMBL30296046 | 0.89 | EDNRA (0.47) | EDNRAAGTR1EDNRB | |
| SCHEMBL30295928 | 0.88 | EDNRA (0.46) | EDNRAAGTR1EDNRB | |
| SCHEMBL4287935 | 0.88 | EDNRA (0.61) | EDNRAAGTR1EDNRB | |
| SCHEMBL30296158 | 0.87 | EDNRA (0.47) | EDNRAAGTR1EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-115745983-A | Angiotensin and endothelin receptor antagonist and application thereof | 深圳信立泰药业股份有限公司 | 2023-03-07 | — | — | CN | disclosed |
| WO-2023025277-A1 | AROMATIC RING-CONTAINING BIOLOGICAL ANTAGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2023-03-02 | — | — | WO | disclosed |