Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 10/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5531210 | 1.00 | EDNRA (0.41) | EDNRAAGTR1EDNRB | |
| SCHEMBL534996 | 0.94 | EDNRA (0.43) | EDNRAAGTR1EDNRB | |
| SCHEMBL5532055 | 0.92 | EDNRA (0.38) | EDNRAAGTR1EDNRB | |
| SCHEMBL30171054 | 0.92 | EDNRA (0.41) | EDNRAAGTR1EDNRB | |
| SCHEMBL5523918 | 0.92 | EDNRA (0.41) | EDNRAAGTR1EDNRB | |
| SCHEMBL30171050 | 0.89 | EDNRA (0.36) | EDNRAAGTR1EDNRB | |
| SCHEMBL13574893 | 0.88 | EDNRA (0.43) | EDNRAAGTR1EDNRB | |
| SCHEMBL30757333 | 0.88 | EDNRA (0.37) | EDNRAAGTR1EDNRB | |
| SCHEMBL4773156 | 0.88 | EDNRA (0.41) | EDNRAAGTR1EDNRB | |
| SCHEMBL5529587 | 0.88 | EDNRA (0.37) | EDNRAAGTR1EDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745983-A | Angiotensin and endothelin receptor antagonist and application thereof | 深圳信立泰药业股份有限公司 | 2023-03-07 | — | — | CN | disclosed |