Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BRD2 | P25440 | 1/20 | 0.31 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29001508 | 1.00 | EDNRB (0.31) | EDNRBEDNRABRD4BRD2BRD3 | |
| SCHEMBL6640127 | 0.88 | EDNRA (0.37) | EDNRBEDNRABRD4 | |
| SCHEMBL30171015 | 0.88 | EDNRA (0.37) | EDNRBEDNRABRD4 | |
| SCHEMBL535004 | 0.82 | GAA (0.33) | — | |
| SCHEMBL30296075 | 0.81 | EDNRA (0.37) | EDNRBEDNRA | |
| SCHEMBL27419866 | 0.81 | EDNRA (0.37) | EDNRBEDNRA | |
| SCHEMBL4773572 | 0.79 | EDNRB (0.35) | EDNRBEDNRA | |
| SCHEMBL4773487 | 0.78 | EDNRB (0.35) | EDNRBEDNRA | |
| SCHEMBL13531528 | 0.78 | — | — | |
| SCHEMBL29799735 | 0.77 | EDNRA (0.40) | EDNRBEDNRABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115745983-A | Angiotensin and endothelin receptor antagonist and application thereof | 深圳信立泰药业股份有限公司 | 2023-03-07 | — | — | CN | disclosed |