Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | GHSR | Q92847 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22728020 | 1.00 | AR (0.63) | ARCYP2C19ABCB11ALBPGR | |
| SCHEMBL19694994 | 1.00 | AR (0.63) | ARCYP2C19ABCB11ALBPGR | |
| SCHEMBL15934329 | 1.00 | AR (0.63) | ARCYP2C19ABCB11ALBPGR | |
| SCHEMBL28374913 | 0.92 | AR (0.56) | ARCYP2C19ABCB11ALBPGR | |
| SCHEMBL29328408 | 0.89 | AR (0.64) | ARCYP2C19ABCB11ALBPGR | |
| SCHEMBL28598515 | 0.86 | AR (0.53) | AR | |
| SCHEMBL22727977 | 0.86 | AR (0.53) | AR | |
| SCHEMBL19287017 | 0.86 | AR (0.53) | AR | |
| SCHEMBL20459116 | 0.86 | AR (0.60) | ARCYP2C19ABCB11ALBPGR | |
| SCHEMBL25166923 | 0.83 | AR (0.55) | ARCYP2C19ABCB11ALBPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115701991-A | Pyrazolylpropionamide compounds and their use for treating prostate cancer | 田纳西大学研究基金会 | 2023-02-14 | — | — | CN | disclosed |
| EP-4125846-A1 | PYRAZOLYLPROPANAMIDE COMPOUNDS AND USES THEREOF FOR TREATMENT OF PROSTATE CANCER | University of Tennessee Research Foundation (US) | 2023-02-08 | — | — | EP | disclosed |