SCHEMBL30171489

SCHEMBL30171489

O=C(c1c(O)c2ccc(-c3ccccc3)cc2oc1=O)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.45
CA9 Q16790 1/20 0.45
HSD11B1 P28845 1/20 0.43
NQO1 P15559 2/20 0.42
ESR1 P03372 2/20 0.41
AR P10275 1/20 0.41
HSD17B3 P37058 1/20 0.41
LMNA P02545 3/20 0.40
ERAP1 Q9NZ08 1/20 0.40
HPGD P15428 1/20 0.40
CCNC P24863 1/20 0.40
CDK8 P49336 1/20 0.40
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 2/20 0.39
MAPT P10636 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MEN1 O00255 1/20 0.39
CYP3A4 P08684 1/20 0.39
ALOX15 P16050 1/20 0.39
CASP1 P29466 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24865018 1.00 CA12 (0.45) CA12CA9HSD11B1NQO1ESR1
SCHEMBL24865044 0.90 CA12 (0.45) CA12CA9HSD11B1NQO1LMNA
SCHEMBL24865045 0.87 CA12 (0.43) CA12CA9HSD11B1NQO1LMNA
SCHEMBL24864745 0.82 CA12 (0.65) CA12CA9NQO1LMNAHPGD
SCHEMBL24864823 0.81 CA12 (0.42) CA12CA9NQO1ESR1AR
SCHEMBL24865046 0.81 ESR1 (0.41) CA12CA9NQO1ESR1HSD17B3
SCHEMBL24865111 0.80 CA12 (0.53) CA12CA9NQO1LMNAHPGD
SCHEMBL24865032 0.80 CA12 (0.41) CA12CA9NQO1ESR1AR
SCHEMBL24864845 0.80 CA12 (0.44) CA12CA9NQO1ESR1AR
SCHEMBL24865047 0.79 MIF (0.43) CA12CA9NQO1LMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023282236-A1 RARE EARTH COMPLEX 東ソー株式会社 2023-01-12 WO disclosed