Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 4/20 | 0.42 |
| ▸ | TTK | P33981 | 12/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.35 |
| ▸ | AURKA | O14965 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22123765 | 0.93 | TTK (0.46) | PTK6TTKGSK3BDYRK1AMAPKAPK5 | |
| SCHEMBL24870826 | 0.92 | PTK6 (0.50) | PTK6TTKAURKBLCK | |
| Hydrochloric Acid SCHEMBL25167713 | 0.92 | TTK (0.45) | PTK6TTKGSK3BDYRK1AMAPKAPK5 | |
| Hydrochloric Acid SCHEMBL30171904 | 0.92 | PTK6 (0.49) | PTK6TTKAURKBLCK | |
| Hydrochloric Acid SCHEMBL30385762 | 0.86 | PTK6 (0.40) | PTK6TTKMAPKAPK5AURKBLCK | |
| SCHEMBL22139088 | 0.85 | TTK (0.44) | PTK6TTKMAPKAPK5AURKBLCK | |
| SCHEMBL22122995 | 0.85 | TTK (0.46) | PTK6TTKAURKBAURKALCK | |
| SCHEMBL25450692 | 0.84 | TTK (0.42) | PTK6TTKMAPKAPK5AURKA | |
| Hydrochloric Acid SCHEMBL30172110 | 0.84 | TTK (0.44) | PTK6TTKMAPKAPK5AURKBLCK | |
| SCHEMBL24870852 | 0.84 | TTK (0.42) | PTK6TTKMAPKAPK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898631-B1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES AS ANTIBACTERIALS | HOFFMANN LA ROCHE (CH) | 2023-01-18 | — | — | EP | disclosed |
| US-20230012368-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2023-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230012368-A1 | NOVEL IMIDAZOPYRAZINE DERIVATIVES | MRPL21, MYD88, IL1R1 | PTK6 2211/4885TTK 4482/4885GSK3B 4630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.