Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 19/20 | 0.69 |
| ▸ | JAK2 | O60674 | 7/20 | 0.69 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28608389 | 1.00 | JAK1 (0.69) | JAK1JAK2HPGDS | |
| SCHEMBL30173344 | 0.88 | JAK1 (0.69) | JAK1JAK2 | |
| SCHEMBL28596869 | 0.88 | JAK1 (0.69) | JAK1JAK2 | |
| SCHEMBL30173268 | 0.88 | JAK1 (0.72) | JAK1JAK2HPGDS | |
| SCHEMBL28603790 | 0.88 | JAK1 (0.72) | JAK1JAK2HPGDS | |
| SCHEMBL28602167 | 0.87 | JAK1 (0.65) | JAK1JAK2HPGDS | |
| SCHEMBL30173303 | 0.87 | JAK1 (0.65) | JAK1JAK2HPGDS | |
| SCHEMBL28602158 | 0.87 | JAK1 (0.65) | JAK1JAK2 | |
| SCHEMBL30173317 | 0.87 | JAK1 (0.65) | JAK1JAK2 | |
| SCHEMBL28606347 | 0.85 | JAK1 (0.69) | JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200983-B | Compound with pyrrolopyridine structure, preparation method and medical application | 中国药科大学 | 2023-01-03 | — | — | CN | disclosed |