Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 3/20 | 0.59 |
| ▸ | AXL | P30530 | 2/20 | 0.59 |
| ▸ | RPS6KA3 | P51812 | 5/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | CCNK | O75909 | 2/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.37 |
| ▸ | AURKA | O14965 | 3/20 | 0.37 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.37 |
| ▸ | TPX2 | Q9ULW0 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 3/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | PAK4 | O96013 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 2/20 | 0.36 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28602125 | 1.00 | PRKCI (0.59) | PRKCIAXLRPS6KA3NUDT1BRD4 | |
| SCHEMBL30173316 | 0.86 | AXL (0.61) | PRKCIAXLRPS6KA3NUDT1CCNK | |
| SCHEMBL28609163 | 0.86 | AXL (0.61) | PRKCIAXLRPS6KA3NUDT1CCNK | |
| SCHEMBL30173348 | 0.81 | PRKCI (0.59) | PRKCIAXLRPS6KA3NUDT1CCNK | |
| SCHEMBL30173347 | 0.81 | PRKCI (0.59) | PRKCIAXLRPS6KA3NUDT1CCNK | |
| SCHEMBL28596854 | 0.81 | PRKCI (0.59) | PRKCIAXLRPS6KA3NUDT1CCNK | |
| SCHEMBL3725709 | 0.80 | JAK2 (0.58) | PRKCIAXLRPS6KA3NUDT1CCNK | |
| SCHEMBL30173305 | 0.80 | JAK2 (0.58) | PRKCIAXLRPS6KA3NUDT1CCNK | |
| SCHEMBL28609105 | 0.78 | PRKCI (0.54) | PRKCIAXLRPS6KA3NUDT1CCNK | |
| SCHEMBL30173333 | 0.78 | PRKCI (0.54) | PRKCIAXLRPS6KA3NUDT1CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200983-B | Compound with pyrrolopyridine structure, preparation method and medical application | 中国药科大学 | 2023-01-03 | — | — | CN | disclosed |