Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 8/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPEPPS | P55786 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29793200 | 0.95 | TYMP (0.42) | TYMPLMNANT5EADORA2AADORA2B | |
| SCHEMBL30173452 | 0.94 | TYMP (0.42) | TYMPLMNANT5EADORA2AADORA2B | |
| SCHEMBL29793043 | 0.91 | TYMP (0.39) | TYMPLMNANT5EADORA2AADORA2B | |
| SCHEMBL30601047 | 0.91 | TYMP (0.43) | TYMPLMNANT5EADORA1 | |
| SCHEMBL29644745 | 0.90 | TYMP (0.42) | TYMPNT5EADORA1 | |
| SCHEMBL29471806 | 0.90 | TYMP (0.42) | TYMPNT5EADORA1 | |
| SCHEMBL18927153 | 0.90 | TYMP (0.42) | TYMPNT5EADORA1 | |
| SCHEMBL18511052 | 0.90 | TYMP (0.42) | TYMPNT5EADORA1 | |
| SCHEMBL31160200 | 0.89 | TYMP (0.43) | TYMPLMNAADORA2AADORA2BSMN1; SMN2 | |
| SCHEMBL29793014 | 0.89 | TYMP (0.43) | TYMPLMNAADORA2AADORA2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023277168-A1 | POLYNUCLEOTIDE AND MEDICINAL COMPOSITION | 協和キリン株式会社 | 2023-01-05 | — | — | WO | disclosed |