⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8651532 | 1.00 | — | — | |
| SCHEMBL544483 | 0.75 | — | — | |
| SCHEMBL29479581 | 0.75 | — | — | |
| SCHEMBL10004646 | 0.75 | — | — | |
| SCHEMBL3361574 | 0.75 | — | — | |
| SCHEMBL30023642 | 0.75 | — | — | |
| SCHEMBL454507 | 0.75 | — | — | |
| SCHEMBL30420165 | 0.75 | — | — | |
| SCHEMBL1577450 | 0.75 | — | — | |
| SCHEMBL28295744 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143187-A1 | COMPOUNDS AND COMPOSITIONS FOR INHIBITING THE ACTIVITY OF HIF2-ALPHA AND THEIR METHODS OF USE | Novartis AG (CH) | 2023-03-08 | — | — | EP | disclosed |