Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL41863 | 1.00 | HIF1A (0.57) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 | |
| Phosphine SCHEMBL28150214 | 0.97 | HIF1A (0.55) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL29563765 | 0.97 | HIF1A (0.60) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 | |
| Iodide SCHEMBL28218736 | 0.95 | HIF1A (0.52) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 | |
| Iodide SCHEMBL28008310 | 0.95 | HIF1A (0.52) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 | |
| Fluoride Ion SCHEMBL584733 | 0.94 | HIF1A (0.57) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 | |
| Water SCHEMBL3419223 | 0.94 | HIF1A (0.57) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL9513351 | 0.94 | HIF1A (0.57) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL29967015 | 0.94 | HIF1A (0.57) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 | |
| Bromide SCHEMBL42887 | 0.94 | HIF1A (0.57) | HIF1ATSHRALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605288-A | Sorbent polymer composite comprising phosphonium halide, flue gas treatment device and flue gas treatment method using same | W.L.戈尔及同仁股份有限公司（US） | 2023-01-13 | — | — | CN | claimed |
| CN-116547054-A | Articles comprising sorbents, polymer composites and halide precursor compositions, methods of adsorbing mercury and sulfur oxides thereon, and methods of producing articles comprising sorbent articles | W.L.戈尔及同仁股份有限公司 | 2023-08-04 | — | — | CN | disclosed |
| US-20230182115-A1 | SORBENT POLYMER COMPOSITES INCLUDING PHOSPHONIUM HALIDES, FLUE GAS TREATMENT DEVICES AND FLUE GAS TREATMENT METHODS UTILIZING THE SAME | W. L. GORE & ASSOCIATES, INC. | 2023-06-15 | — | — | US | disclosed |
| EP-4149671-A1 | SORBENT POLYMER COMPOSITES INCLUDING PHOPHONIUM HALIDES, FLUE GAS TREATMENT DEVICES AND FLUE GAS TREATMENT METHODS UTILIZING THE SAME | W. L. Gore & Associates, Inc. (US) | 2023-03-22 | — | — | EP | disclosed |
| CN-115605288-A | Sorbent polymer composite comprising phosphonium halide, flue gas treatment device and flue gas treatment method using same | W.L.戈尔及同仁股份有限公司（US） | 2023-01-13 | — | — | CN | disclosed |