Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23782350 | 1.00 | SMN1; SMN2 (0.66) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL4109577 | 0.83 | PTPN1 (0.61) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL30848609 | 0.83 | PTPN1 (0.61) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL12123751 | 0.82 | SMN1; SMN2 (0.57) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL27491739 | 0.82 | KMT2A (0.51) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL30848559 | 0.81 | SMN1; SMN2 (0.73) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL4108418 | 0.81 | SMN1; SMN2 (0.73) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL12123748 | 0.80 | SMN1; SMN2 (0.60) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL8536512 | 0.79 | SMN1; SMN2 (1.00) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 | |
| SCHEMBL12123908 | 0.78 | SMN1; SMN2 (0.59) | SMN1; SMN2KDM4EHPGDNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115515685-B | EIF4E inhibitors and uses thereof | 皮克医疗公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-115515685-A | EIF4E inhibitor and application thereof | 皮克医疗公司 | 2022-12-23 | — | — | CN | disclosed |