Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.65 |
| ▸ | PIK3R2 | O00459 | 20/20 | 0.65 |
| ▸ | PIK3CA | P42336 | 20/20 | 0.65 |
| ▸ | PIK3CB | P42338 | 20/20 | 0.65 |
| ▸ | PIK3CG | P48736 | 20/20 | 0.65 |
| ▸ | PIK3R5 | Q8WYR1 | 20/20 | 0.65 |
| ▸ | PIK3R3 | Q92569 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24188784 | 1.00 | PIK3CD (0.65) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL24188644 | 0.93 | PIK3CD (0.66) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL30308388 | 0.93 | PIK3CD (0.66) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL14814 | 0.91 | PIK3CD (0.78) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL31568734 | 0.91 | PIK3CD (0.78) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL30308352 | 0.91 | PIK3CD (0.64) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL24189190 | 0.91 | PIK3CD (0.64) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL29515210 | 0.89 | PIK3CD (0.64) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL25883887 | 0.89 | PIK3CD (0.64) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG | |
| SCHEMBL24189240 | 0.89 | PIK3CD (0.61) | PIK3CDPIK3R2PIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115836077-B | Oxazaspiro derivative, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-113754685-B | Dihydrothiochromene pyrazole derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-115835863-A | Oxaazabicyclic derivatives, preparation method and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-113754678-B | Dihydrothiochromene pyrazole derivative, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-03-10 | — | — | CN | disclosed |