SCHEMBL30175309

SCHEMBL30175309

CC(O)COc1ccc2c(C#N)cnn2c1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ RET P07949 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31458875 1.00 RET (0.47) RET
SCHEMBL30175340 0.90 RET (0.43) RET
SCHEMBL31458768 0.88 RET (0.47) RET
SCHEMBL30248760 0.86 RET (0.50) RET
SCHEMBL30175295 0.84 RET (0.41) RET
SCHEMBL29566683 0.82 RET (0.45) RET
Hydrochloric Acid SCHEMBL28993707 0.81 RET (0.44) RET
SCHEMBL30175296 0.80 RET (0.45) RET
SCHEMBL30175294 0.80 RET (0.43) RET
SCHEMBL30175335 0.80 RET (0.37) RET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114163437-B Substituted pyrazolo [1,5-a ] pyridine compounds as RET kinase inhibitors 阿雷生物药品公司 2025-03-04 — — CN disclosed
CN-115605477-B Pyrazolo [1,5-a ] pyridine derivative, preparation method, composition and application thereof 深圳众格生物科技有限公司 2024-07-05 — — CN disclosed
CN-115605477-A Pyrazolo [1,5-a ] pyridine derivative and preparation method, composition and application thereof 深圳众格生物科技有限公司(CN) 2023-01-13 — — CN disclosed
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