Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.42 |
| ▸ | RET | P07949 | 17/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | KIF5B | P33176 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CCDC6 | Q16204 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25560641 | 1.00 | EGLN1 (0.42) | EGLN1RETTDO2JAK2FLT3 | |
| SCHEMBL17966627 | 1.00 | EGLN1 (0.42) | EGLN1RETTDO2JAK2FLT3 | |
| SCHEMBL30175375 | 1.00 | EGLN1 (0.42) | EGLN1RETTDO2JAK2FLT3 | |
| SCHEMBL18789230 | 1.00 | EGLN1 (0.42) | EGLN1RETTDO2JAK2FLT3 | |
| SCHEMBL17966637 | 1.00 | EGLN1 (0.42) | EGLN1RETTDO2JAK2FLT3 | |
| Hydrochloric Acid SCHEMBL29501567 | 0.98 | EGLN1 (0.41) | EGLN1RETTDO2JAK2FLT3 | |
| Hydrochloric Acid SCHEMBL28604580 | 0.98 | EGLN1 (0.41) | EGLN1RETTDO2JAK2FLT3 | |
| Hydrochloric Acid SCHEMBL18789240 | 0.98 | EGLN1 (0.41) | EGLN1RETTDO2JAK2FLT3 | |
| Hydrochloric Acid SCHEMBL28608786 | 0.98 | EGLN1 (0.41) | EGLN1RETTDO2JAK2FLT3 | |
| Hydrochloric Acid SCHEMBL28430937 | 0.98 | EGLN1 (0.41) | EGLN1RETTDO2JAK2FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605477-B | Pyrazolo [1,5-a ] pyridine derivative, preparation method, composition and application thereof | 深圳众格生物科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-111423416-B | Inhibitors of RET | 缆图药品公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-115605477-A | Pyrazolo [1,5-a ] pyridine derivative and preparation method, composition and application thereof | 深圳众格生物科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |