SCHEMBL30175900

SCHEMBL30175900

CC(C)(C)OC(=O)Nc1ccc(Br)cc1NC(=O)OC(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 12/20 0.49
NPC1 O15118 1/20 0.47
RECQL P46063 1/20 0.47
RAB9A P51151 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HPGD P15428 1/20 0.46
KCNQ4 P56696 1/20 0.44
KCNQ5 Q9NR82 1/20 0.44
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
CYP17A1 P05093 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1519234 1.00 AAK1 (0.49) AAK1NPC1RECQLRAB9ASMN1; SMN2
SCHEMBL10006006 0.94 AAK1 (0.46) AAK1NPC1RECQLRAB9ASMN1; SMN2
SCHEMBL30273933 0.91 AAK1 (0.46) AAK1NPC1RECQLRAB9ASMN1; SMN2
SCHEMBL24509457 0.89 AAK1 (0.48) AAK1NPC1RECQLRAB9ASMN1; SMN2
SCHEMBL1647601 0.88 CYP17A1 (0.51) AAK1NPC1RECQLRAB9ASMN1; SMN2
SCHEMBL13514632 0.87 AAK1 (0.47) AAK1NPC1RECQLRAB9ASMN1; SMN2
SCHEMBL29991534 0.87 AAK1 (0.49) AAK1NPC1RECQLRAB9ASMN1; SMN2
SCHEMBL31167627 0.87 AAK1 (0.52) AAK1NPC1RAB9ASMN1; SMN2HPGD
SCHEMBL6176599 0.87 AAK1 (0.47) AAK1NPC1RECQLRAB9ASMN1; SMN2
SCHEMBL456674 0.87 AAK1 (0.49) AAK1NPC1RECQLRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-29 US disclosed
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-20 US disclosed
US-20220352477-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240074301-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP AAK1 2926/4885NPC1 1839/4885RECQL 2967/4885
US-20220352477-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP AAK1 2926/4885NPC1 1839/4885RECQL 2967/4885
US-20230120996-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ICOSLG, OCIAD2, OSBP AAK1 2926/4885NPC1 1839/4885RECQL 2967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.