Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23782522 | 1.00 | DHODH (0.39) | DHODHNOS2RORCF10PRSS1 | |
| SCHEMBL23782610 | 0.92 | MEN1 (0.43) | DHODHRORCMEN1KMT2APTGDR2 | |
| SCHEMBL30173803 | 0.92 | MEN1 (0.43) | DHODHRORCMEN1KMT2APTGDR2 | |
| SCHEMBL30176202 | 0.88 | DHODH (0.40) | DHODHNOS2F10PRSS1ADORA2A | |
| SCHEMBL23782489 | 0.88 | DHODH (0.40) | DHODHNOS2F10PRSS1ADORA2A | |
| SCHEMBL23782339 | 0.86 | DHODH (0.39) | DHODHNOS2F10PRSS1ADORA2A | |
| SCHEMBL23782486 | 0.86 | DHODH (0.44) | DHODHNOS2F10PRSS1ADORA2A | |
| SCHEMBL23782599 | 0.86 | DHODH (0.38) | DHODHNOS2F10PRSS1MEN1 | |
| SCHEMBL23792704 | 0.84 | PTGDR2 (0.40) | DHODHRORCMEN1KMT2APTGDR2 | |
| SCHEMBL23792693 | 0.84 | FDFT1 (0.39) | DHODHRORCMEN1KMT2APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4114529-A1 | EIF4E INHIBITORS AND USES THEREOF | PIC Therapeutics, Inc. (US) | 2023-01-11 | — | — | EP | disclosed |