SCHEMBL30176435

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)C(C)C)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	VIPR1	P32241	5/20	0.69

▸	VIPR2	P41587	7/20	0.66

▸	GLP1R	P43220	2/20	0.66

▸	GCGR	P47871	1/20	0.66

▸	GIPR	P48546	1/20	0.66

▸	CCKBR	P32239	1/20	0.64

▸	TFPI	P10646	1/20	0.62

▸	NPY2R	P49146	6/20	0.60

▸	NPY4R	P50391	6/20	0.60

▸	NPY5R	Q15761	6/20	0.60

▸	NPY1R	P25929	4/20	0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30432804	0.95	VIPR1 (0.70)	VIPR1VIPR2GLP1RGCGRGIPR
SCHEMBL30607451	0.94	VIPR1 (0.69)	VIPR1VIPR2GLP1RGCGRGIPR
SCHEMBL29496440	0.93	VIPR1 (0.71)	VIPR1VIPR2GLP1RGCGRGIPR
SCHEMBL29403715	0.92	VIPR1 (0.72)	VIPR1VIPR2GLP1RGCGRGIPR
SCHEMBL30495755	0.92	VIPR1 (0.65)	VIPR1VIPR2GLP1RGCGRGIPR
SCHEMBL30437423	0.92	VIPR1 (0.61)	VIPR1VIPR2GLP1RGCGRGIPR
SCHEMBL29357155	0.92	GLP1R (0.64)	VIPR1VIPR2GLP1RGCGRGIPR
SCHEMBL29694509	0.92	VIPR2 (0.66)	VIPR1VIPR2TFPINPY2RNPY4R
SCHEMBL30432173	0.91	VIPR1 (0.69)	VIPR1VIPR2GLP1RGCGRGIPR
SCHEMBL31182595	0.91	GLP1R (0.68)	VIPR1VIPR2GLP1RGCGRGIPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230272394-A1	RNA-DIRECTED DNA CLEAVAGE BY THE Cas9-crRNA COMPLEX	VILNIUS UNIVERSITY (LT)	2023-08-31	—	—	US	disclosed
US-11555187-B2	RNA-directed DNA cleavage by the Cas9-crRNA complex	VILNIUS UNIVERSITY (LT)	2023-01-17	—	—	US	disclosed