SCHEMBL30176444

CC[C@H](C)[C@H](NC(=O)CNC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](N)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)CC)[C@@H](C)CC)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(C)C)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	14/20	0.56

▸	HCRTR1	O43613	1/20	0.56

▸	HCRTR2	O43614	1/20	0.56

▸	CALCR	P30988	4/20	0.55

▸	CRHR1	P34998	1/20	0.54

▸	CRHR2	Q13324	1/20	0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL29903321	0.89	GLP1R (0.69)	GLP1R
SCHEMBL31073542	0.89	CALCR (0.58)	GLP1RHCRTR1HCRTR2CALCRCRHR1
SCHEMBL30432115	0.88	VIPR2 (0.60)	GLP1RCALCRCRHR1CRHR2
SCHEMBL29461469	0.88	CALCR (0.55)	GLP1RCALCRCRHR1CRHR2
SCHEMBL29967663	0.87	GLP1R (0.64)	GLP1RCALCRCRHR1CRHR2
SCHEMBL29680082	0.87	GLP1R (0.51)	GLP1RHCRTR1HCRTR2CALCRCRHR1
SCHEMBL30168776	0.87	CALCR (0.61)	GLP1RHCRTR1HCRTR2CALCRCRHR1
SCHEMBL30175851	0.86	GLP1R (0.61)	GLP1R
SCHEMBL31603933	0.86	GLP1R (0.69)	GLP1R
SCHEMBL31454237	0.86	GLP1R (0.68)	GLP1RCALCRCRHR1CRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230272394-A1	RNA-DIRECTED DNA CLEAVAGE BY THE Cas9-crRNA COMPLEX	VILNIUS UNIVERSITY (LT)	2023-08-31	—	—	US	disclosed
US-11555187-B2	RNA-directed DNA cleavage by the Cas9-crRNA complex	VILNIUS UNIVERSITY (LT)	2023-01-17	—	—	US	disclosed