SCHEMBL30176459

CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@@H](N)CS)[C@@H](C)O)[C@@H](C)CC)C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C)C(=O)O)C(C)C)[C@@H](C)O

nearest known ligand 0.69

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	4/20	0.69

▸	NPY1R	P25929	1/20	0.65

▸	NPY2R	P49146	1/20	0.65

▸	NPY4R	P50391	1/20	0.65

▸	NPY5R	Q15761	1/20	0.65

▸	GLP1R	P43220	13/20	0.63

▸	CCKBR	P32239	4/20	0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30176434	0.98	CALCR (0.70)	CALCRNPY1RNPY2RNPY4RNPY5R
SCHEMBL30712940	0.91	GLP1R (0.68)	CALCRNPY1RNPY2RNPY4RNPY5R
SCHEMBL31182647	0.91	NPY1R (0.72)	CALCRNPY1RNPY2RNPY4RNPY5R
SCHEMBL31182892	0.91	CALCR (0.66)	CALCRNPY1RNPY2RNPY4RNPY5R
SCHEMBL30658334	0.90	CALCR (0.65)	CALCRNPY1RNPY2RNPY4RNPY5R
SCHEMBL30567706	0.90	GLP1R (0.70)	CALCRNPY1RNPY2RNPY4RNPY5R
SCHEMBL30906422	0.89	NPY1R (0.68)	CALCRNPY1RNPY2RNPY4RNPY5R
SCHEMBL29679866	0.89	NPY1R (0.72)	CALCRNPY1RNPY2RNPY4RNPY5R
SCHEMBL30690369	0.89	CALCR (0.66)	CALCRNPY1RNPY2RNPY4RNPY5R
SCHEMBL30690333	0.89	CALCR (0.66)	CALCRNPY1RNPY2RNPY4RNPY5R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230272394-A1	RNA-DIRECTED DNA CLEAVAGE BY THE Cas9-crRNA COMPLEX	VILNIUS UNIVERSITY (LT)	2023-08-31	—	—	US	disclosed
US-11555187-B2	RNA-directed DNA cleavage by the Cas9-crRNA complex	VILNIUS UNIVERSITY (LT)	2023-01-17	—	—	US	disclosed