SCHEMBL30176470

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCNC(=N)N)[C@@H](C)O)[C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCSC)C(=O)O

nearest known ligand 0.76

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	CALCR	P30988	4/20	0.73

▸	CRHR1	P34998	1/20	0.70

▸	CRHR2	Q13324	1/20	0.70

▸	F2	P00734	4/20	0.69

▸	GLP1R	P43220	4/20	0.66

▸	GCGR	P47871	3/20	0.66

▸	NPY2R	P49146	5/20	0.63

▸	NPY4R	P50391	5/20	0.63

▸	NPY5R	Q15761	5/20	0.63

▸	NPY1R	P25929	3/20	0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30658284	0.93	CALCR (0.76)	CALCRCRHR1CRHR2F2GLP1R
SCHEMBL30884870	0.93	CALCR (0.75)	CALCRCRHR1CRHR2GLP1RGCGR
SCHEMBL30432505	0.93	GLP1R (0.66)	CALCRCRHR1CRHR2GLP1R
SCHEMBL29949373	0.92	CALCR (0.70)	CALCRCRHR1CRHR2GLP1RGCGR
SCHEMBL30432038	0.92	CALCR (0.72)	CALCRCRHR1CRHR2F2GLP1R
SCHEMBL29767063	0.92	CALCR (0.79)	CALCRCRHR1CRHR2GLP1RGCGR
SCHEMBL31745603	0.92	CALCR (0.72)	CALCRCRHR1CRHR2GLP1RGCGR
SCHEMBL30932066	0.91	CALCR (0.77)	CALCRCRHR1CRHR2GLP1RGCGR
SCHEMBL31182545	0.91	CALCR (0.75)	CALCRCRHR1CRHR2GLP1RGCGR
SCHEMBL29939723	0.91	CALCR (0.79)	CALCRCRHR1CRHR2GLP1RGCGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20230272394-A1	RNA-DIRECTED DNA CLEAVAGE BY THE Cas9-crRNA COMPLEX	VILNIUS UNIVERSITY (LT)	2023-08-31	—	—	US	disclosed
US-11555187-B2	RNA-directed DNA cleavage by the Cas9-crRNA complex	VILNIUS UNIVERSITY (LT)	2023-01-17	—	—	US	disclosed